Proteomic Identification of Nrf2-Mediated Phase II Enzymes Critical for Protection of Tao Hong Si Wu Decoction against Oxygen Glucose Deprivation Injury in PC12 Cells
Figure 1
Cytotoxicity and protective effect of THSWD in PC12 cells. (a) Cytotoxicity of THSWD. PC12 cells were treated with THSWD at concentrations ranging from 0 to 2 mg·mL−1 for 24 h. (b) Effect of THSWD on the cell survival of PC12 cells against OGD-Rep. PC12 cells were pretreated with THSWD at concentrations ranging from 0 to 1.5 mg·mL−1 for 2 h, subsequently subjected to OGD-Rep treatment for 8 h, and finally maintained in oxygenated cell culture medium for another 18 h. The cell viability was determined by CCK-8 assay. Values represent mean ± SD (). versus OGD-Rep.
