Treatment Effects of Xuebijing Injection in Severe Septic Patients with Disseminated Intravascular Coagulation

Table 3

Incidence of DIC, clinical severity scores, and coagulation parameters at 7 days after administration of Xuebijing injection.

	Control group (𝑛=83)	Intervention group (𝑛=88)	𝑃
DIC (𝑛, %)	22 (26.51)	5 (5.68)	<0.001
Platelet (×10^9/L)	119.15±91.24	131.95±88.36	0.205
PT (s)	21.52±14.81	17.2±8	0.003
Fibrinogen (g/L)	3.65±1.63	3.67±1.56	0.183
D-dimer (mg/L)	3.72 (1.26–6.37)	3.45 (1.12–5.87)	0.743
INR	1.65±0.83	1.65±0.93	0.997
MEDS score	8 (5–18)	7 (4–15)	0.039
APACHE II score	14 (11–27)	13 (10–25)	0.107

DIC: disseminated intravascular coagulation; MEDS score: Mortality in Emergency Department Sepsis score; APACHE II score: Acute Physiology and Chronic Health Evaluation II score; PT: prothrombin time; INR: international normalized ratio.