Treatment Effects of Xuebijing Injection in Severe Septic Patients with Disseminated Intravascular Coagulation

Table 4

Differences of clinical severity scores and coagulation parameters (values at baseline minus values at 7 days after administration of Xuebijing injection).

	Control group (𝑛=83)	Intervention group (𝑛=88)	𝑃
Platelet (×10^9/L)	−38.95±76.06	−61.44±81.84	0.005
PT (s)	4.25±6.32	5.46±7.36	0.036
Fibrinogen (g/L)	−0.99±4.38	−1.11±4.08	0.563
D-dimer (mg/L)	1.24±2.02	1.63±2.21	0.138
INR	0.16±0.65	0.08±0.73	0.472
MEDS score	2.05±3.98	3.85±4.63	0.007
APACHE II score	7.18±8.97	10.63±9.17	0.014

MEDS score: Mortality in Emergency Department Sepsis score; APACHE II score: Acute Physiology and Chronic Health Evaluation II score; PT: prothrombin time; INR: international normalized ratio.