Antiviral Activity of Total Flavonoid Extracts from Selaginella moellendorffii Hieron against Coxsackie Virus B3 In Vitro and In Vivo

Table 3

Virus titers of heart and kidney in CBV3-infected mice (-lgTCID50).

Groups	Heart	Kidney
Normal control	0	0
Virus control	4.3 ± 0.3	5.3 ± 0.4
TFE-100 mg/kg	3.5 ± 0.3*	3.9 ± 0.3**
TFE-300 mg/kg	1.9 ± 0.2**	2.4 ± 0.1**
TFE-900 mg/kg	1.2 ± 0.1**	1.6 ± 0.2**
ACV-10 mg/kg	4.2 ± 0.2	5.4 ± 0.3

All the viral titers data present in a format of -lgTCID₅₀. Values are means ± SD (n = 10). ∗P < 0.05 and ∗∗P < 0.01, compared with the virus control group.