Xanthoceraside Ameliorates Mitochondrial Dysfunction Contributing to the Improvement of Learning and Memory Impairment in Mice with Intracerebroventricular Injection of A𝜷1-42

Figure 9

Effects of xanthoceraside on PDHC and KGDHC activity in isolated cerebral cortex mitochondria of A𝛽1-42-induced mice. (a) The activity of PDHC and (b) the activity of KGDHC. The data are presented as means ± SEM (𝑛=7-8). ^##𝑃<0.01 compared with control group; ^∗∗𝑃<0.01, ^∗𝑃<0.05 compared with model group. PDHC: pyruvate dehydrogenase complex; KGDHC: 𝛼-ketoglutarate dehydrogenase complex.

(a)

(b)