Evaluation of Antioxidant Activity and Acute Toxicity of Clausena excavata Leaves Extract

Figure 4

Liver treated with methanolic extract of Clausena excavata. (a) and (b) Normal hepatocytes, parenchyma, and central vein, respectively. (c) and (d) Liver (low dose; 2000 mg/kg, male and female rats) showing mononuclear cell infiltrations and congestion of the central vein (arrows). (e) and (f) Liver (high dose; 5000 mg/kg, male and female rats) showing infiltration of kupffer cells, vascular congestion, and mild periportal necrosis. (H&E, ×200).

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