Research Article

Triptolide Attenuates Podocyte Injury by Regulating Expression of miRNA-344b-3p and miRNA-30b-3p in Rats with Adriamycin-Induced Nephropathy

Table 1

Upregulated miRNAs in the model group compared with the normal group.

IDNameFold change valueFDR

46917rno-miR-2051.92457 0.00000 0.00459
11074rno-miR-34c-5p2.29828 0.00029 0.07672
148480rno-miR-494-5p2.76551 0.01961 0.27645
148099rno-miR-344b-3p1.52253 0.03831 0.29845
46210rno-miR-12491.91770 0.01733 0.26785
29190rno-miR-708-5p3.01526 0.00164 0.14709
29153rno-miR-34b-5p2.78153 0.01647 0.26294
42723rno-miR-195-3p2.19307 0.01701 0.26686
14288rno-miR-503-5p2.43302 0.00351 0.17969
29575rno-miR-32-3p2.21251 0.04169 0.30459
168586rno-miR-34a-5p4.43281 0.00000 0.00248
42694rno-miR-485-3p3.08079 0.00089 0.13137
148343rno-miR-35681.94418 0.03106 0.29127
27558rno-miR-155-5p2.53069 0.03852 0.29845
168968rno-miR-1473.65262 0.02648 0.28483
13150rno-miR-322-5p1.54620 0.00811 0.23523
42626rno-miR-30b-3p3.18227 0.01956 0.27645
148139rno-miR-3596c2.77024 0.00653 0.20639
148068rno-miR-758-5p1.92262 0.00069 0.12406

ID: array ID of the probes; each miRNA always has its unique probe; name: the name of each miRNA; fold change: the ratio of normalized intensities between two conditions (use normalized data, ratio scale); value: -test result between samples in different groups; FDR: FDR is calculated from Benjamini Hochberg FDR. Fold change cutoff: 1.5; value cutoff: 0.05.