Evaluation of Antidiabetic Effects of the Traditional Medicinal Plant Gynostemma pentaphyllum and the Possible Mechanisms of Insulin Release

Figure 1

(a) The effects of treatment with Gynostemma pentaphyllum (GP) (0.3 g/kg of body weight) in GK rat () on (a) blood glucose level in the oral glucose tolerance test, GP-treated (---) or placebo (—), (b) area under the glucose curves in the oral glucose tolerance test , GP versus Placebo. (c) Plasma insulin levels in GP-treated group compared to placebo group at 0, 30, and 120 min in the oral glucose tolerance test. (GP-treated group versus placebo group at 0 min), (GP-treated group versus placebo group at 30 and 120 min resp.). (d) Insulin secretion (when compared with the placebo group at 16.7 mM glucose). All data are presented as means ± SEM and analyzed using unpaired -test.

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