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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 120981, 6 pages
http://dx.doi.org/10.1155/2015/120981
Research Article

Fucoidans Disrupt Adherence of Helicobacter pylori to AGS Cells In Vitro

The Marshall Centre for Infectious Diseases Research and Training, School of Pathology and Laboratory Medicine (M502), The University of Western Australia, 35 Stirling Highway, Nedlands, WA 6009, Australia

Received 13 August 2015; Revised 11 October 2015; Accepted 12 October 2015

Academic Editor: Svein Haavik

Copyright © 2015 Eng-Guan Chua et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Y. Gao, C. Li, J. Yin et al., “Fucoidan, a sulfated polysaccharide from brown algae, improves cognitive impairment induced by infusion of Aβ peptide in rats,” Environmental Toxicology and Pharmacology, vol. 33, no. 2, pp. 304–311, 2012. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Abdollahi, A. Morteza, O. Khalilzadeh, A. Zandieh, and M. Asgarshirazi, “The role of Helicobacter pylori infection in gastro-oesophageal reflux in Iranian children,” Annals of Tropical Paediatrics, vol. 31, no. 1, pp. 53–57, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. A. Beress, O. Wassermann, T. Bruhn et al., “A new procedure for the isolation of anti-HIV compounds (polysaccharides and polyphenols) from the marine alga Fucus vesiculosus,” Journal of Natural Products, vol. 56, no. 4, pp. 478–488, 1993. View at Google Scholar · View at Scopus
  4. S. Szabo, S. Kusstatscher, Z. Sandor, and G. Sakoulas, “Molecular and cellular basis of ulcer healing,” Scandinavian Journal of Gastroenterology, vol. 30, no. 208, pp. 3–8, 1995. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Juffrie, I. Rosalina, W. Damayanti, A. Djumhana, A. Ariani, and H. Ahmad, “The efficacy of fucoidan on gastric ulcer,” Indonesian Journal of Biotechnology, vol. 11, no. 2, pp. 908–913, 2006. View at Google Scholar
  6. A. Cumashi, N. A. Ushakova, M. E. Preobrazhenskaya et al., “A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds,” Glycobiology, vol. 17, no. 5, pp. 541–552, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. K. O. U. Hayakawa and T. Nagamine, “Effect of fucoidan on the biotinidase kinetics in human hepatocellular carcinoma,” Anticancer Research, vol. 29, no. 4, pp. 1211–1218, 2009. View at Google Scholar · View at Scopus
  8. I. Hirai, T. Sasaki, A. Kimoto, S. Fujimoto, T. Moriyama, and Y. Yamamoto, “Assessment of East Asian-type cagA-positive Helicobacter pylori using stool specimens from asymptomatic healthy Japanese individuals,” Journal of Medical Microbiology, vol. 58, no. 9, pp. 1149–1153, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. J. H. Fitton, “Therapies from fucoidan; multifunctional marine polymers,” Marine Drugs, vol. 9, no. 10, pp. 1731–1760, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. V. H. Pomin, “Fucanomics and galactanomics: marine distribution, medicinal impact, conceptions, and challenges,” Marine Drugs, vol. 10, no. 4, pp. 793–811, 2012. View at Publisher · View at Google Scholar · View at Scopus
  11. K. R. Sridhar and N. Vidyavathi, “Antimicrobial activity of seaweeds,” Acta Hydrochimica et Hydrobiologica, vol. 19, no. 5, pp. 455–496, 1991. View at Publisher · View at Google Scholar
  12. A. Bennamara, A. Abourriche, M. Berrada et al., “Methoxybifurcarenone: an antifungal and antibacterial meroditerpenoid from the brown alga Cystoseira tamariscifolia,” Phytochemistry, vol. 52, no. 1, pp. 37–40, 1999. View at Publisher · View at Google Scholar · View at Scopus
  13. L.-Y. Li, L.-Q. Li, and C.-H. Guo, “Evaluation of in vitro antioxidant and antibacterial activities of Laminaria japonica polysaccharides,” Journal of Medicinal Plants Research, vol. 4, no. 21, pp. 2194–2198, 2010. View at Google Scholar · View at Scopus
  14. S. Hirmo, M. Utt, M. Ringner, and T. Wadström, “Inhibition of heparan sulphate and other glycosaminoglycans binding to Helicobacter pylori by various polysulphated carbohydrates,” FEMS Immunology& Medical Microbiology, vol. 10, no. 3-4, pp. 301–306, 1995. View at Publisher · View at Google Scholar · View at Scopus
  15. E. Ruiz-Bustos, J. L. Ochoa, T. Wadström, and F. Ascencio, “Isolation and characterisation of putative adhesins from Helicobacter pylori with affinity for heparan sulphate proteoglycan,” Journal of Medical Microbiology, vol. 50, no. 3, pp. 215–222, 2001. View at Publisher · View at Google Scholar · View at Scopus
  16. N. Lutay, I. Nilsson, T. Wadström, and Å. Ljungh, “Effect of heparin, fucoidan and other polysaccharides on adhesion of enterohepatic helicobacter species to murine macrophages,” Applied Biochemistry and Biotechnology, vol. 164, no. 1, pp. 1–9, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. B. J. Marshall and H. M. Windsor, “The relation of Helicobacter pylori to gastric adenocarcinoma and lymphoma: pathophysiology, epidemiology, screening, clinical presentation, treatment, and prevention,” Medical Clinics of North America, vol. 89, no. 2, pp. 313–344, 2005. View at Publisher · View at Google Scholar · View at Scopus
  18. P. Malfertheiner, F. Megraud, C. A. O'Morain et al., “Management of Helicobacter pylori infection—the maastricht IV/florence consensus report,” Gut, vol. 61, no. 5, pp. 646–664, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. E. Rimbara, L. A. Fischbach, and D. Y. Graham, “Optimal therapy for Helicobacter pylori infections,” Nature Reviews Gastroenterology and Hepatology, vol. 8, no. 2, pp. 79–88, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. F. Mégraud, “H pylori antibiotic resistance: prevalence, importance, and advances in testing,” Gut, vol. 53, no. 9, pp. 1374–1384, 2004. View at Publisher · View at Google Scholar · View at Scopus
  21. N. Horiki, F. Omata, M. Uemura et al., “Annual change of primary resistance to clarithromycin among helicobacter pylori isolates from 1996 through 2008 in Japan,” Helicobacter, vol. 14, no. 5, pp. 86–90, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. D. Y. Graham and L. Fischbach, “Helicobacter pylori treatment in the era of increasing antibiotic resistance,” Gut, vol. 59, no. 8, pp. 1143–1153, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. C. Y. Tay, H. M. Windsor, F. Thirriot et al., “Helicobacter pylori eradication in Western Australia using novel quadruple therapy combinations,” Alimentary Pharmacology and Therapeutics, vol. 36, no. 11-12, pp. 1076–1083, 2012. View at Publisher · View at Google Scholar · View at Scopus
  24. M. Dubois, K. A. Gilles, J. K. Hamilton, P. A. Rebers, and F. Smith, “Colorimetric method for determination of sugars and related substances,” Analytical Chemistry, vol. 28, no. 3, pp. 350–356, 1956. View at Publisher · View at Google Scholar · View at Scopus
  25. K. S. Dodgson, “Determination of inorganic sulphate in studies on the enzymic and non-enzymic hydrolysis of carbohydrate and other sulphate esters,” Biochemical Journal, vol. 78, pp. 312–319, 1961. View at Publisher · View at Google Scholar · View at Scopus
  26. K. S. Dodgson and R. G. Price, “A note on the determination of the ester sulphate content of sulphated polysaccharides,” The Biochemical Journal, vol. 84, pp. 106–110, 1962. View at Publisher · View at Google Scholar · View at Scopus
  27. B. W. Zoecklein, K. C. Fugelsang, B. H. Gump, and F. S. Nury, Wine Analysis and Production, Chapman and Hall, New York, NY, USA, 1995. View at Publisher · View at Google Scholar
  28. A. Jiménez-Escrig, I. Jiménez-Jiménez, R. Pulido, and F. Saura-Calixto, “Antioxidant activity of fresh and processed edible seaweeds,” Journal of the Science of Food and Agriculture, vol. 81, no. 5, pp. 530–534, 2001. View at Publisher · View at Google Scholar · View at Scopus
  29. Q. Zhang, J. Zhang, J. Shen, A. Silva, D. A. Dennis, and C. J. Barrow, “A simple 96-well microplate method for estimation of total polyphenol content in seaweeds,” Journal of Applied Phycology, vol. 18, no. 3–5, pp. 445–450, 2006. View at Publisher · View at Google Scholar · View at Scopus
  30. M. Morvai-Vitányi, I. Molnár-Perl, D. Knausz, and P. Sass, “Simultaneous GC derivatization and quantification of acids and sugars,” Chromatographia, vol. 36, no. 1, pp. 204–206, 1993. View at Publisher · View at Google Scholar · View at Scopus
  31. V. K. Morya, J. Kim, and E.-K. Kim, “Algal fucoidan: structural and size-dependent bioactivities and their perspectives,” Applied Microbiology and Biotechnology, vol. 93, no. 1, pp. 71–82, 2012. View at Publisher · View at Google Scholar · View at Scopus
  32. K.-Y. Lee, M.-R. Jeong, S.-M. Choi, S.-S. Na, and J.-D. Cha, “Synergistic effect of fucoidan with antibiotics against oral pathogenic bacteria,” Archives of Oral Biology, vol. 58, no. 5, pp. 482–492, 2013. View at Publisher · View at Google Scholar · View at Scopus
  33. C. Zhuang, H. Itoh, T. Mizuno, and H. Ito, “Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii),” Bioscience, Biotechnology, and Biochemistry, vol. 59, no. 4, pp. 563–567, 1995. View at Publisher · View at Google Scholar · View at Scopus
  34. H. Maruyama, H. Tamauchi, M. Hashimoto, and T. Nakano, “Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida,” In Vivo, vol. 17, no. 3, pp. 245–249, 2003. View at Google Scholar · View at Scopus
  35. T. V. Alekseyenko, S. Y. Zhanayeva, A. A. Venediktova et al., “Antitumor and antimetastatic activity of fucoidan, a sulfated polysaccharide isolated from the Okhotsk sea Fucus evanescens brown alga,” Bulletin of Experimental Biology and Medicine, vol. 143, no. 6, pp. 730–732, 2007. View at Publisher · View at Google Scholar · View at Scopus
  36. S. Fukahori, H. Yano, J. Akiba et al., “Fucoidan, a major component of brown seaweed, prohibits the growth of human cancer cell lines in vitro,” Molecular Medicine Reports, vol. 1, no. 4, pp. 537–542, 2008. View at Google Scholar · View at Scopus
  37. J.-H. Hyun, S.-C. Kim, J.-I. Kang et al., “Apoptosis inducing activity of fucoidan in HCT-15 colon carcinoma cells,” Biological and Pharmaceutical Bulletin, vol. 32, no. 10, pp. 1760–1764, 2009. View at Publisher · View at Google Scholar · View at Scopus
  38. E. J. Kim, S. Y. Park, J.-Y. Lee, and J. H. Y. Park, “Fucoidan present in brown algae induces apoptosis of human colon cancer cells,” BMC Gastroenterology, vol. 10, article 96, 2010. View at Publisher · View at Google Scholar · View at Scopus
  39. M. T. Ale, H. Maruyama, H. Tamauchi, J. D. Mikkelsen, and A. S. Meyer, “Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo,” International Journal of Biological Macromolecules, vol. 49, no. 3, pp. 331–336, 2011. View at Publisher · View at Google Scholar · View at Scopus
  40. H.-J. Boo, J.-H. Hyun, S.-C. Kim et al., “Fucoidan from Undaria pinnatifida induces apoptosis in A549 human lung carcinoma cells,” Phytotherapy Research, vol. 25, no. 7, pp. 1082–1086, 2011. View at Publisher · View at Google Scholar · View at Scopus
  41. C. Korzeniewski and D. M. Callewaert, “An enzyme-release assay for natural cytotoxicity,” Journal of Immunological Methods, vol. 64, no. 3, pp. 313–320, 1983. View at Publisher · View at Google Scholar · View at Scopus
  42. H. S. Park, G.-Y. Kim, T.-J. Nam, N. Deuk Kim, and Y. Hyun Choi, “Antiproliferative activity of fucoidan was associated with the induction of apoptosis and autophagy in AGS human gastric cancer cells,” Journal of Food Science, vol. 76, no. 3, pp. 77–83, 2011. View at Publisher · View at Google Scholar · View at Scopus
  43. D. Lamoral-Theys, L. Pottier, F. Dufrasne et al., “Natural polyphenols that display anticancer properties through inhibition of kinase activity,” Current Medicinal Chemistry, vol. 17, no. 9, pp. 812–825, 2010. View at Publisher · View at Google Scholar · View at Scopus
  44. H. Shibata, I. Kimura-Takagi, M. Nagaoka et al., “Inhibitory effect of Cladosiphon fucoidan on the adhesion of Helicobacter pylori to human gastric cells,” Journal of Nutritional Science and Vitaminology, vol. 45, no. 3, pp. 325–336, 1999. View at Publisher · View at Google Scholar · View at Scopus
  45. N. Araya, K. Takahashi, T. Sato et al., “Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type-1-associated neurological disease,” Antiviral Therapy, vol. 16, no. 1, pp. 89–98, 2011. View at Publisher · View at Google Scholar · View at Scopus