Research Article

A Pilot Study: The Efficacy of Virgin Coconut Oil as Ocular Rewetting Agent on Rabbit Eyes

Table 1

Mean (±SD) for study eyes at each time point using different types of drops. (Agent I: VCO, agent II: saline, and agent III: Tears Naturale II.)

Mean (±SD)Agent0 min30 min60 min2 weeks

NIBUTI20.76 ± 2.3619.71 ± 2.1020.26 ± 2.2620.61 ± 1.96
II22.52 ± 2.6022.34 ± 3.5922.44 ± 3.0523.40 ± 3.30
III22.70 ± 1.5723.71 ± 2.2424.31 ± 3.0324.31 ± 3.29

Corneal stainingI0.83 ± 0.291.00 ± 0.001.00 ± 0.001.00 ± 0.00
II1.00 ± 0.001.00 ± 0.001.00 ± 0.001.00 ± 0.00
III1.00 ± 0.001.00 ± 0.001.00 ± 0.000.83 ± 0.29

Limbal hyperemiaI0.83 ± 0.291.00 ± 0.001.00 ± 0.001.00 ± 0.00
II1.00 ± 0.001.00 ± 0.001.00 ± 0.001.00 ± 0.00
III1.00 ± 0.001.00 ± 0.001.00 ± 0.000.83 ± 0.29

Conjunctival hyperemiaI0.83 ± 0.291.33 ± 0.291.50 ± 0.001.00 ± 0.00
II0.67 ± 0.581.50 ± 0.001.50 ± 0.000.50 ± 0.50
III1.00 ± 0.001.00 ± 0.001.00 ± 0.000.83 ± 0.29

Palpebral hyperemiaI0.83 ± 0.291.33 ± 0.291.50 ± 0.001.00 ± 0.00
II0.67 ± 0.581.50 ± 0.001.50 ± 0.000.50 ± 0.50
III1.00 ± 0.001.17 ± 0.291.33 ± 0.290.83 ± 0.29

Schirmer testI1.00 ± 0.001.33 ± 0.291.33 ± 0.291.00 ± 0.00
II0.67 ± 0.580.67 ± 0.580.83 ± 0.761.00 ± 0.50
III1.00 ± 0.001.00 ± 0.001.00 ± 0.000.83 ± 0.29

pHI7.67 ± 0.197.67 ± 0.387.89 ± 0.228.00 ± 0.39
II7.34 ± 1.457.67 ± 0.387.67 ± 0.197.56 ± 1.06
III6.66 ± 0.886.67 ± 0.967.22 ± 0.737.11 ± 0.22