Research Article

Germinated Brown Rice Alters Aβ(1-42) Aggregation and Modulates Alzheimer’s Disease-Related Genes in Differentiated Human SH-SY5Y Cells

Figure 6

Proposed schematic diagram showing targets of germinated brown rice (GBR) in APP processing metabolism pathway. ADAM10: a disintegrin and metalloproteinase domain-containing protein 10; APP: amyloid precursor protein; BACE: beta-site APP-cleaving enzyme; Bax: BCL2-associated X protein; H2O2: hydrogen peroxide; JNK: c-Jun N-terminal kinases; LRP: low density lipoprotein receptor-related protein; p53: p53 tumor suppressor.