Review Article

Jingtong Granule: A Chinese Patent Medicine for Cervical Radiculopathy

Table 1

Summary of the included studies in the review.

First author (year)Sample size (T/C)Population characteristicsInterventionComparisonDuration of treatmentOutcome assessmentConclusion

Liu, 2008 [37]120 (84/36)Age: 21 to 60
(T/C: NA)
Course: NA
JG (4 g, Tid, PO)Placebo
(300 mg, Tid, PO)
T: 28 days
C: 28 days
VAS (0 to 100)
Diff: 18.53
The results suggested JG was better than placebo for reductions of pain in the treatment of CR.

Jin, 2008 [38]120 (60/60)Age: 27 to 59
(T/C: NA)
Course: 3 hours to 5 days
(T/C: NA)
JG (4 g, Tid, PO) + CFirst three days: 20% mannitol (250 mL, Ivgtt, Qd) + dexamethasone (10 mg, Ivgtt, Qd)
After three days: 20% mannitol (250 mL, Ivgtt, Qd) + dexamethasone (5 mg, Ivgtt, Qd)
T: 6 days
C: 6 days
VAS (0 to 10)
Diff: 1.75
The result of randomized controlled clinical trial showed that both JG and western medicine therapies were effective and superior to single western medicine in relieving pain for CR.

Liu, 2013 [39]160 (80/80)Age: 26 to 66
(T: 26 to 66; C: 30 to 65)
Course: 3 months to 5 years
(T/C: 3 months to 5 years)
JG (4 g, Qd, PO) + CICST
(2 pills/time, Bid)
T: 14 days (JC)
C: 5 days
VAS (0 to 10)
Diff: 1.30
NDI
Diff: 8.40
The improvements in VAS and NDI scores difference of intervention group were better than those of the control group.

T: treatment group; C: control group; Diff: difference between before and after treatment in both groups; NA: not reported.
JG: Jingtong granule; ICST: ibuprofen codeine sustained tablets.
Tid: three times a day; Bid: twice a day; Qd: once a day; PO: oral administration; Ivgtt: intravenous guttae.
VAS: visual analogue scale; NDI: neck disability index; CR: cervical radiculopathy.