In Vitro and In Vivo Antitumor Effects of n-Butanol Extracts of Pterocephalus hookeri on Hep3B Cancer Cell

Figure 6

YSC-ZDC inhibited growth hepatoma xenografts in vivo. Hep3B cells (10⁶ cells/200 μL) were subcutaneously injected into the left flank of the mice. Indicated doses of YSC-ZDC were administered via gavage daily for 20 days. 5-FU was dissolved in 0.9% normal saline and administered intraperitoneally (20 mg/kg/day) for 2-day intervals as a positive control group. After 20 days, the mice were sacrificed and Hep3B xenograft tumors were excised and photographed. (a) Tumor volumes. (b) Tumor weight. (c) Body weight. (d) The spleen index (SI, spleen/body weight). Data are shown as means ± S.E.M. ^*, ^** versus vehicle.

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