Pharmacological and Genotoxic Properties of Polyphenolic Extracts of Cedrela odorata L. and Juglans regia L. Barks in Rodents

Table 1

Concentration of phenolic compounds and antioxidant capacity in C. odorata and J. regia bark extracts.

Solvent	Yield %	TP; mg GAE/g extract	TF; mg CE/g extract	PAC; mg CE/g extract	DPPH (EC50); µg/mL	-Carotene; (% AA)
Cedrela odorata
Water	5.07	203.2 ± 18.0^a	94.3 ± 10.3^a	144.6 ± 16.1^a	1385.4 ± 31.8^a	7.1 ± 0.5^a
Ethanol 96%	2.28	332.4 ± 10.9^b	144.3 ± 10.3^b	180.0 ± 9.1^ab	645.5 ± 22.0^b	9.5 ± 0.5^b
Ethanol 70%	5.89	549.6 ± 20.7^c	144.6 ± 10.5^b	266.7 ± 10.7^c	654.2 ± 21.9^b	10.4 ± 0.3^c
Ethyl acetate	1.30	304.9 ± 12.1^d	186.4 ± 19.7^c	313.2 ± 11.3^c	739.1 ± 54.4^c	9.5 ± 0.5^b
Juglans regia
Water	21.40	405.7 ± 23.0^e	257.4 ± 17.0^d	198.7 ± 2.7^b	517.7 ± 12.2^d	14.0 ± 3.8^d
Ethanol 96%	6.76	577.3 ± 24.9^c	296.5 ± 10.0^e	538.9 ± 72.6^d	323.2 ± 4.0^e	13.4 ± 1.4^d
Ethanol 70%	10.54	570.3 ± 13.4^c	321.2 ± 15.8^e	548.7 ± 59.0^d	373.8 ± 4.9^e	12.5 ± 0.9^e
Ethyl acetate	1.05	568.7 ± 15.3^c	374.8 ± 7.6^f	443.0 ± 24.0^e	331.2 ± 4.7^e	14.1 ± 1.0^d

Each value represents the mean of   ± standard deviation. Different letters between groups in each column indicate a significant difference () assessed using the Fisher-LSD test.