Research Article

Protective Effects of Tao-Hong-Si-Wu Decoction on Memory Impairment and Hippocampal Damage in Animal Model of Vascular Dementia

Table 3

The mean optical density of Bcl-2 and Bax in hippocampus CA1 after immunostaining.

GroupDose (g/kg)Bcl-2 mean optical density valuesBax mean optical density valuesBcl-2/Bax

Sham0.191 ± 0.007*0.158 ± 0.011**1.215 ± 0.110**
Model0.202 ± 0.0050.406 ± 0.0140.498 ± 0.025
TSD180.290 ± 0.016**0.202 ± 0.016**1.443 ± 0.127**
TSD90.239 ± 0.013**0.278 ± 0.012**0.863 ± 0.071**
TSD4.50.213 ± 0.0110.374 ± 0.019*0.569 ± 0.015**
Nimodipine0.020.251 ± 0.008**0.216 ± 0.017**1.169 ± 0.119**

All data are mean ± S.D., . *, ** compared with model group.