Research Article
Protective Effects of Tao-Hong-Si-Wu Decoction on Memory Impairment and Hippocampal Damage in Animal Model of Vascular Dementia
Table 3
The mean optical density of Bcl-2 and Bax in hippocampus CA1 after immunostaining.
| Group | Dose (g/kg) | Bcl-2 mean optical density values | Bax mean optical density values | Bcl-2/Bax |
| Sham | — | 0.191 ± 0.007* | 0.158 ± 0.011** | 1.215 ± 0.110** | Model | — | 0.202 ± 0.005 | 0.406 ± 0.014 | 0.498 ± 0.025 | TSD | 18 | 0.290 ± 0.016** | 0.202 ± 0.016** | 1.443 ± 0.127** | TSD | 9 | 0.239 ± 0.013** | 0.278 ± 0.012** | 0.863 ± 0.071** | TSD | 4.5 | 0.213 ± 0.011 | 0.374 ± 0.019* | 0.569 ± 0.015** | Nimodipine | 0.02 | 0.251 ± 0.008** | 0.216 ± 0.017** | 1.169 ± 0.119** |
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All data are mean ± S.D., . *, ** compared with model group.
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