Tualang Honey Protects against BPA-Induced Morphological Abnormalities and Disruption of ERα, ERβ, and C3 mRNA and Protein Expressions in the Uterus of Rats

Figure 5

Representative sections of uteri showing the immunohistological localization of ERα in all experimental groups (×40). The most pronounced immunostaining intensity in both control ((C), (D)) (NC groups) and Tualang honey treated alone ((G), (H)) (THC groups) rats. Lower immunostaining intensity in BPA-exposed rats ((E), (F)) (PC group) was observed. Concurrent treatment with Tualang honey TH group ((I), (J)) also showed similar immunostaining intensity with these BPA-exposed rats.

(a) Negative control (vehicle) without primary antibody

(b) Negative control (vehicle)

(c) Positive control (BPA 10 mg/kg)

(d) Tualang honey control (Tualang honey 200 mg/kg)

(e) Tualang honey (Tualang honey 200 mg/kg + BPA 10 mg/kg)