Randomized Clinical Trial of the Innovative Bilayered Wound Dressing Made of Silk and Gelatin: Safety and Efficacy Tests Using a Split-Thickness Skin Graft Model

Table 2

Erythema and melanin levels of healthy volunteers’ skin at the beginning phase, induction phase I, induction phase II, and challenge phase.

	Beginning phase	Induction phase I	Induction phase II	Challenge phase
Erythema level
Bactigras	233.57 ± 81.96	218.93 ± 78.44	217.31 ± 78.49	219.45 ± 75.60
Bilayered wound dressing	243.70 ± 85.09	233.17 ± 83.47	230.86 ± 82.75	231.82 ± 79.91
Melanin level
Bactigras	226.47 ± 97.65	216.22 ± 95.03	216.30 ± 95.13	216.28 ± 95.09
Bilayered wound dressing	234.89 ± 101.84	224.64 ± 100.17	224.69 ± 99.93	224.64 ± 99.97

Significant differences ( versus beginning phase), calculated by repeated measures ANOVA.