Antrodia camphorata Potentiates Neuroprotection against Cerebral Ischemia in Rats via Downregulation of iNOS/HO-1/Bax and Activated Caspase-3 and Inhibition of Hydroxyl Radical Formation

Figure 1

Effects of the extracts of A. camphorata combined with aspirin on the expressions of iNOS in cerebral homogenates 24 h after thromboembolic stroke in rats. Fresh brains from each group rats were removed and sectioned coronally into four sequential parts of the frontal lobe to the occipital lobe. The third of four sequential parts of the ischemic-injured hemisphere was separately collected, homogenized, and centrifuged. The supernatant (50 μg protein) was then subjected to SDS-PAGE and transferred onto membranes for analysis of iNOS expressions. Data are presented as the mean ± S.E.M. , compared to the sham-operated group, and , compared to the MCAO group.