Strong Manual Acupuncture Stimulation of “Huantiao” (GB 30) Reduces Pain-Induced Anxiety and p-ERK in the Anterior Cingulate Cortex in a Rat Model of Neuropathic Pain

Figure 2

Anxiety-like behaviors in the elevated zero maze during a 5 min test session on day 12 after L5 spinal nerve ligation. (a) Total distance (, ); (b) distance in open arms (, ); (c) time in open arms (, ); (d) resting time in open arms (, ); (e) image of detection; ((f)-(g)) analysis graphics of trace. Each column represents the mean ± SEM of six animals per group. , versus control group; , versus SNL group.

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