Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Fig 5

Research Article

Artocarpin Induces Apoptosis in Human Cutaneous Squamous Cell Carcinoma HSC-1 Cells and Its Cytotoxic Activity Is Dependent on Protein-Nutrient Concentration

Figure 5

Time-dependent changes in the concentration of artocarpin in (a) HSC-1 cells (intracellular compartment) and (b) culture medium (extracellular compartment) under different concentrations of FBS. Artocarpin concentration in the two different compartments was determined by HPLC-UV analysis after treatment of cells with artocarpin (10 μM) for different periods of time. Results are mean ± SEM of 3 independent experiments.