The Th17/Treg Immune Balance in Ulcerative Colitis Patients with Two Different Chinese Syndromes: Dampness-Heat in Large Intestine and Spleen and Kidney Yang Deficiency Syndrome
Table 1
Clinical data in DHLI syndrome and SKYD syndrome groups.
Characteristics
DHLI group ()
SKYD group ()
value
Male
26 (57.8)
21 (45.7)
0.291
Age-year
0.192
Medication history
SASP
5 (11.11)
6 (13.33)
1.000
5-ASA
19 (42.22)
21 (46.67)
0.416
TCM
11 (24.45)
7 (15.56)
0.430
Integrative treatment
10 (22.22)
11 (24.45)
1.000
Disease type
Initial onset type#
13 (28.9)
2 (3.4)
0.002
Chronic persistent type
15 (33.3)
19 (42.2)
0.384
Chronic relapsing type
17 (37.8)
24 (53.3)
0.138
Active phase#
31 (68.9)
19 (42.2)
0.011
Remission phase#
14 (31.1)
26 (57.7)
0.011
Disease level
Mild
12 (26.7)
16 (35.6)
0.362
Middle
29 (64.5)
28 (62.2)
0.827
Severe
4 (6.9)
1 (2.2)
0.167
Duration of disease
⩽60 months#
19 (42.2)
10 (22.2)
0.042
>60 months#
26 (57.8)
35 (77.8)
0.042
Clinical activity index#
7.4 ± 2.3
6.4 ± 2.1
0.036
Endoscopic index#
6.0 ± 2.2
4.8 ± 1.7
0.010
Biopsy type☆
0
8 (17.8)
11 (24.4)
0.438
1
10 (22.2)
8 (17.8)
0.598
2
12 (26.7)
13 (28.9)
0.814
3
8 (17.8)
7 (15.6)
0.777
4
3 (6.7)
4 (8.9)
0.694
5
4 (8.9)
2 (4.4)
0.398
Data was presented as case number (%). Age, clinical activity index, and endoscopic index were displayed as mean ± SD.
#. There was significant difference between the DHLI and SKYD groups. ☆0, structural change only; 1, chronic inflammation; 2, lamina propria neutrophils; 3, neutrophils in epithelium; 4, crypt destruction; and 5, erosions or ulcers [18].
