Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Fig 5

Research Article

1,2,3,4,6-Penta-O-galloylglucose within Galla Chinensis Inhibits Human LDH-A and Attenuates Cell Proliferation in MDA-MB-231 Breast Cancer Cells

Figure 5

(a) hLDH-A (0.02 units/mL) enzyme inhibition by PGG. The data represent hLDH-A activity as % control (NADH oxidation) at 60 minutes and are expressed as the mean ± SEM, with significance from controls determined with a one-way ANOVA followed by Bonferroni’s multiple comparison test; , . IC50 = 27.17 nM. (b) hLDH-A enzyme inhibition by reference known inhibitor (oxalic acid). The data represent hLDH-A activity as % control (NADH oxidation) at 60 minutes and are expressed as the mean ± SEM, with significance from controls determined using a one-way ANOVA followed by Bonferroni’s multiple comparison test; , , IC50 > 6 mM.
(a)
(b)

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