Protective Effects of Scutellarin on Human Cardiac Microvascular Endothelial Cells against Hypoxia-Reoxygenation Injury and Its Possible Target-Related Proteins

Table 2

Differentially-expressed proteins found in proteomic analysis of nuclei/membrane protein expression profiles of different groups and results of MS/MS identification.

Spot	Target protein name	Accession number of NCBI database	Theoretical Mr (Da)/pI	Protein score	Sequence coverage (%)	Best ion score	Spot volume (ppm)		Fold change
							CT group	HR group	HR/CT
1	Eukaryotic translation initiation factor 3, subunit 12, isoform CRA_b	119577208	17921/6.02	110	21	70	614.7 ± 423	182.1 ± 211.9	0.30
2	Albumin-like	763431	52048/5.69	138	9	86	831 ± 784	1997.7 ± 1131.4	2.41
3	p27BBP protein	13785574	26332/4.56	290	27	121	1868.7 ± 1220.8	726.1 ± 822.6	0.39
							CT group	SCU group	SCU/CT
4	Chain A, structural and electrophysiological analysis of annexin V mutants	157831406	35782/4.98	128	18	44	725.4 ± 314.8	241.7 ± 273.7	0.33
5	ATPase, H+ transporting, lysosomal 56/58 kDa, V1 subunit B2, isoform CRA_a	119584163	56465/5.57	87	15	31	584.1 ± 613.7	74.3 ± 126.8	0.13
6	VLA-3 alpha subunit	220141	113433/6.13	118	15	32	1812.1 ± 1377.5	536.9 ± 482.8	0.30
7	Eukaryotic translation elongation factor 1 gamma, isoform CRA_d	119594432	48407/6.24	187	28	47	4283.8 ± 2973.2	1790.3 ± 1335.2	0.42
							HR group	SCU + HR group	SCU + HR/HR
3	p27BBP protein	13785574	26332/4.56	290	27	121	726.1 ± 822.6	1797.3 ± 1085.5	2.48