Evidence-Based Complementary and Alternative Medicine

Research Article

Antiviral Action of Hydromethanolic Extract of Geopropolis from Scaptotrigona postica against Antiherpes Simplex Virus (HSV-1)

Table 1

Results obtained by RPHPLC-DAD-ESI-MS/MS analyses of geopropolis from Scaptotrigona postica: retention times (Rt), MS data for positive ion mode, and structure proposed.


	Rt	[M + Na]⁺	[M + H]⁺	Structure proposed

1	3.9	—	[M + H]⁺ 443 MS/MS—291	Catechin-3-O-gallate

2	5.6	[M + Na]⁺—365	[M + H]⁺—343	Caffeoyl glucoside

3	6.5		[M + H]⁺—415 MS/MS—397 (100), 379 (40), 361 (30), 331 (50)	7-Methoxy-5-hydroxy-8-C-flavone rhamnoside

4	15.5		[M + H]⁺ 430 MS/MS—412 (100), 385 (70), 367 (10), 315 (20)	7(3-Methoxy-2-methylbutyryl)-9-echimidinylretronecine or methoxy echimidine derivative

5	16.0		[M + H]⁺ 444 MS/MS—426 (100), 399 (20)	7(3-Ethoxy-2-methylbutyryl)-9-echimidinylretronecine or ethoxy echimidine derivative

6	16.5		[M + H]⁺ 619 MS/MS—601 (80), 583 (20), 565 (20), 535 (100)	Acacetin-di-C-acetyl dirhamnoside

7	17.9	[M + Na]⁺ 865	[M + H]⁺ 843 MS/MS—825 (100), 807 (40), 789 (20), 771 (30), 723 (60), 705 (50)	Apigenin-6,8-di-C-malonyl glucoside dihexoside isomer

8	19.2	[M + Na]⁺ 865	[M + H]⁺ 843 MS/MS—825 (80), 807 (40), 789 (30), 771 (20), 723 (70), 705 (100), 687 (40)	Apigenin-6,8-di-C-malonyl glucoside dihexoside isomer

9	20.2	[M + Na]⁺ 865	[M + H]⁺ 843 MS/MS—825 (100), 807 (50), 789 (20), 771 (30), 723 (60), 705 (70), 687 (40)	Apigenin-di-C-malonyl trihexoside isomer

10	20.4		[M + H]⁺ 857 MS/MS—839 (100), 803 (30), 737 (40), 719 (30)	Acacetin-di-C-malonyl trihexoside

11	21.1	[M + Na]⁺ 865	[M + H]⁺ 843 MS/MS—825 (90), 807 (50), 789 (30), 771 (25), 723 (100), 705 (60), 687 (10)	Apigenin-di-C-malonyl trihexoside isomer

12	22.6		[M + H]⁺ 563 MS/MS—417	Acacetin-8-C-arabinoside-7-O-rhamnoside

13	24.5	M + Na]⁺ 865	M + H]⁺ 843 MS/MS—825 (100), 807 (50), 789 (10), 771 (20), 723 (70), 705 (60)	apigenin-di-C-malonyl trihexoside isomer

14	27.0	[M + Na]⁺ 617 MS/MS—599 (100), 581 (20)	[M + H]⁺ 595 MS/MS—577 (100), 559 (30), 541 (20), 529 (40), 511 (50), 499 (30), 475 (30), 457 (60)	Vicenin-2

15	27.5	[M + Na]⁺—445 MS/MS—427 (100), 409 (18)	[M + H]⁺—423 MS/MS—405 (100), 387 (30), 369 (30), 357 (60), 327 (30)	Catechin arabinoside

16	28.0	[M + Na]⁺ 459 MS/MS—441	[M + H]⁺—437 MS/MS—419 (100), 401 (20), 383 (10), 371 (40), 341 (20)	Catechin rhamnoside

17	28.5		[M + H]⁺ 565 MS/MS—547 (100), 529 (70), 511 (50), 427 (60)	Apigenin-6,8-di-C-arabinoside glucoside

18	29.4		[M + H]⁺ 547 MS/MS—401	Chrysin-8-C-rhamnoside-7-O-rhamnoside

19	29.8		[M + H]⁺ 517 MS/MS—355 (80), 337 (100)	3,5-Dicaffeoyl quinic acid

20	31.0		[M + H]⁺ 595 MS/MS—577 (100), 567 (70), 551 (90)	Luteolin-8-C-caffeoyl rhamnoside

21	33.4		[M + H]⁺ 487	Caffeoylquinic acid-O-arabinoside