Neuropharmacological Potential of Gastrodia elata Blume and Its Components

Figure 2

(a) Experimental scheme used to evaluate the effect of vanillin in a trimethyltin- (TMT-) induced seizure model. Mice received a single injection of TMT (2.6 mg/kg, intraperitoneal (i.p.)) and vanillin (100 mg/kg, i.p.) once daily for 3 days at −1 day, 0 days, and 1 day relative to TMT injection. Behavioral changes used to measure seizure activity were observed and scored 1, 2, and 3 days after TMT injection. (b) The anticonvulsant effect of vanillin against TMT-induced clinical seizure symptoms in C57BL/6 mice. Data are presented as means ± standard errors of the mean (SEM). , versus TMT-treated group.

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