Prophylactic Treatment with Adlay Bran Extract Reduces the Risk of Severe Acute Radiation Dermatitis: A Prospective, Randomized, Double-Blind Study
Table 4
Multivariate analysis to determine prognostic factors for the development of severe acute radiation dermatitis (RTOG grade ≥ 2) ().
Factor
Adjusted odds ratio
95% CI
value
Age
1.00
0.95–1.05
0.964
Body mass index
1.31
1.11–1.56
0.002
Diabetes mellitus
3.95
0.55–28.27
0.172
Hypertension
0.96
0.20–4.62
0.955
Pretreatment hemoglobin level
0.91
0.59–1.38
0.645
Pretreatment creatinine level
1.77
0.51–6.12
0.368
Surgery (MRM versus BCS)
0.82
0.26–2.60
0.736
Chemotherapy before radiotherapy
0.44
0.13–1.49
0.189
Hormone therapy
1.02
0.39–2.69
0.963
Intervention (adlay bran versus placebo)
0.24
0.09–0.63
0.004
Multivariate analysis was performed using logistic regression. MRM: modified radical mastectomy, BCS: breast conserving surgery, and CI: confidence interval.
