Neuroprotective Effect of Radix Trichosanthis Saponins on Subarachnoid Hemorrhage

Figure 8

RT saponins inhibition of p53 expression after SAH. (A) Evaluation of p53 expression in SAH mice by immunohistochemical assay (×400). After RT saponins pretreatment, positive p53 staining in SAH was decreased; (B) quantification of p53 level by densitometry. At least 10 visual fields were captured and more than 500 cells were counted. The quantification represents means and standard deviations of results from three independent experiments. versus sham; versus SAH.