Application of Antrodia camphorata Promotes Rat’s Wound Healing In Vivo and Facilitates Fibroblast Cell Proliferation In Vitro

Table 1

Effect of Antrodia camphorata extract on percentage (%) wound healing in experimental rats.

Groups	Doses	Day 0	Day 7		Day 14
	Twice daily	Wound area mm^2	Wound area mm^2	Closure %	Wound area mm^2	Closure %
Gum acacia	0.2 mL/kg	340.00 ± 4.36	180.33 ± 8.69	47.06	76.00 ± 8.33	77.65
Antrodia camphorata	100 mg/kg	338.33 ± 3.71	149.67 ± 6.17	55.92	37.00 ± 5.57	89.05
	200 mg/kg	337.67 ± 4.84	146.33 ± 4.91	56.68	33.67 ± 4.81	90.21
Intrasite gel	0.2 mL/kg	336.67 ± 4.84	129.33 ± 6.98	61.61	36.67 ± 7.45	89.29

Statistical analysis of the data was carried out using one-way analysis of variance (ANOVA) and Tukey’s post hoc test for average comparison on SPSS 18.0. Mean values ± SEM were used. Significance was defined as < 0.05 compared to gum acacia group.