Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Tab 1

Research Article

Sagunja-Tang Improves Lipid Related Disease in a Postmenopausal Rat Model and HepG2 Cells

Table 1

Metabolic parameters in a rat model of menopausal hyperlipidemia.

ShamOVX-ConOVX-SVOVX-SGJT (50)OVX-SGJT (150)OVX-SGJT (450)
(n = 5)(n = 5)(n = 5)(n = 5)(n = 5)(n = 5)

Body weight gain (g)96.44 ± 4.8117.34 ± 1.985.74 ± 3.0d109.40 ± 2.3b92.12 ± 2.5c96.02 ± 2.7c
Food intake (g/day)57.60 ± 18.90a58.65 ± 18.75a53.30 ± 14.40a54.25 ± 14.95a53.85 ± 15.15a55.20 ± 15.70a
Liver weight (g)7.673 ± 0.41317.510 ± 1.35115.609 ± 1.043a16.080 ± 1.467a17.361 ± 1.032a17.598 ± 1.094a
Retroperitoneal fat (mm)119.03 ± 8.56217.96 ± 18.08108.02 ± 6.81b86.11 ± 4.45b95.08 ± 6.85b95.99 ± 4.52b
Perirenal fat (mm)89.4355 ± 1.67233.87 ± 10.10100.37 ± 11.64b81.45 ± 6.63b84.99 ± 5.49b94.85 ± 3.37b

Sham, Sham rats fed a high-fat (HFD), high-cholesterol diet (HCD); OVX-Con, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD); OVX-SV, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD) supplemented with simvastatin (20 mg/kg); OVX-SGJT, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD) supplemented with SGJT (50, 150, 450 mg/kg). After 8 weeks, body, and liver weights (g) and retroperitoneal fat and peri-renal fat sizes (mm) were measured. Values are expressed as means ± SD (n = 5). Significantly different between the sham and OVX-Con at P < 0.01, (two-sample -test). Values not sharing a common alphabet as superscripts are significantly different from each other at the level of P < 0.05 (ANOVA followed by Duncan’s test).

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