Review Article

Acupuncture for Low Back Pain: An Overview of Systematic Reviews

Table 1

Characteristics of systematic reviews.

Authors (date)/
country
ConditionNumber of RCTs (patients) includedQuality of original studies scale/levelAcu style of SRAcu adequacy assessment of original studiesQuality of SR Data analysis methodsComparisonsReported resultsAuthors conclusions/comments [notes]
Pain reliefFunctional improvement

Lee et al.
(2013) [16]/Korea
Acute NSLBP11 (1139)2009 CBRGC and additional criteria
(5/11)
Low
TCM, Western Judged by two experts about two questions6Meta-
analysis
(1) Sham acu
(2) Medications
+
#
=
NR
Acupuncture may be more effective than medication for symptom improvement or relieve pain better than sham acupuncture in acute NSLBP/include Asian database. Strict criteria of being high quality studies. Emphasize the impact of language restriction and Chinese studies [overall improvement (+) compared to medications]

Lam et al. (2013) [17]/IrelandChronic NSLBP32 (5931)Cochrane risk of bias tool
(7/32)
Low
TCMNR6Meta-
analysis
(1) Sham acu
(2) No treatment
(3) Plus usual care
(4) Medications
(5) TENS
+
+
+
+
=
=
+
+
+
NR
Acupuncture may have a favorable effect on pain and function on chronic NSLBP/high heterogeneity of included studies. Confused subgroups. Clear definition of clinical significance.

Wu et al.
(2013) [18]/China
LIDH6 (540)Cochrane risk of bias tool
(NR)
Low
TCMNR5Meta-
analysis
Various controls (oral medications, traction, medication injection, or transfusion)=NRAcupuncture is effective and safe for LIDH/article in Chinese. Restricted publication status. No subgroup comparison provided. Quality of evidence evaluated by GRADE [noneffectiveness rate (−)]

Xu et al.
(2013) [19]/China
Chronic LBP13 (2678)2003
CBRGC
(12/13)
High
NRNR5Meta-
analysis
(1) No treatment
(2) Conventional therapy
(3) Sham acu
+
+
=
+
+
=
Acupuncture is an effective treatment for chronic LBP but may due to nonspecific effects/exclude Asian database other than Chinese. No key studies characteristics provided [no treatment group included blank treatment comparison]

Furlan et al.
(2012) [20]/
Canada
LBP33 (NR)2009
CBRGC (NR)
NR
NRNR5Meta-
analysis
For acute/subacute NSLBP
(1) Sham acu
For chronic NSLBP
(1) Sham therapy
(2) No treatment
(3) Medications
(4) Manipulation
(5) Usual care
  
=

+
+
=

+
  
=

=
+
=
NR
+
Same as reported results/not specific to acupuncture. No studies characteristics provided. Quality of evidence evaluated by GRADE.

Li et al.
(2010) [21]/China
LIDH5 (718)Jadad (2/5)
Low
TCM (electro)NR5Meta-
analysis
Various controls (oral medications or physiotherapy)+NRElectroacupuncture is effective and safe for LIDH/article in Chinese. Restricted publication status. No subgroup comparison provided. Poor quality of meta-analysis (repeatedly pooled the same study in one analysis) [effective rate (+)]

Rubinstein et al.
(2010) [22]/Netherlands
Chronic NSLBP20 (5590)2003
CBRGC
(8/20)
Low
TCMNR5Meta-
analysis
(1) Sham therapy
(2) No treatment
(3) Plus conventional therapy
(4) Usual acre
+
+
+
+
+
+
+
+
Acupuncture provides short-term clinically relevant effects when compared with no treatment or added to other therapies/not specific to acupuncture. No studies characteristics provided. No heterogeneity present. Quality of evidence evaluated by GRADE.

Machado et al. (2009) [23]/AustraliaNSLBP4 (149)PEDro
(4/4)
High
NRNR3Meta-
analysis
Placebo controls=NRAcupuncture is not more effective than placebo/not specific to acupuncture. No studies characteristics provided. No heterogeneity present.

Ammendolia
et al. (2008) [24]/
Canada
Chronic LBP19 (5001)2003 CBRGC
(10/19)
Low
TCM, WesternNR4Best-evidence synthesis(1) Waiting list
(2) Plus conventional therapy
(3) Conventional therapy
(4) Sham therapy
+
+
=
#
+
+
=
=
Same as reported results/lack rigorous format of SR.

Yuan et al. (2008) [25]/UKNSLBP23 (6359)2003 CBRGC and additional criteria (6/23)
Low
TCM, WesternCompared to textbooks, surveys, and primary reviews4Meta-
analysis, best-evidence synthesis
(1) No treatment
(2) Plus Conventional therapy
(3) Sham acu
(4) Conventional therapy
+
+
=
#
+
+
=
#
Acupuncture versus no treatment and as an adjunct to conventional care should be advocated in the European Guidelines for chronic LBP/exclude non-English articles. No heterogeneity present. No overall effect size of pooled studies provided. Strict criteria of being high quality studies. Clear definition of clinical significance.

Li et al. (2008) [26]/ChinaLIDH5 (547)Jüni
(NR)
High
TCM (electro)NR7Meta-
analysis
Various controls (oral medications or physiotherapy)++Electroacupuncture is effective and safe for LIDH/article in Chinese. No subgroup comparison provided.

Keller et al.
(2007) [27]/Norway
NSLBP7 (528)2003 CBRGC and Jadad
(NR)
High
NRNR2Meta-
analysis
Various controls (sham therapy or no treatment)+NRAcupuncture has modest effect for chronic LBP/not specific to acupuncture. No subgroup comparison provided.

Manheimer et al. (2005) [28]/USALBP33 (2300)1997 CBRGC and Jadad
(12/33, 17/33)
Low
TCM, WesternNR8Meta-
analysis
For acute LBP
For chronic LBP
(1) Sham acu
(2) No treatment
(3) Conventional therapy
(4) Manipulation


+
+



=
+

Acupuncture effectively relieves chronic low back pain. No evidence suggests acupuncture is more effective than other active therapies/exclude Chinese database. Restricted publication status. Clear definition of clinical significance.

Furlan et al. (2005) [29]/CanadaNSLBP35 (2861)2003 CBRGC
(14/35)
Low
TCM, WesternJudged by three experienced acupuncturists based on four questions9Meta-
analysis, best-evidence synthesis
For acute NSLBP
For chronic NSLBP
(1) Sham therapy
(2) No treatment
(3) Plus conventional therapy
(4) Conventional therapy


+
+
+
=


=
+
+
=
No firm conclusions for acute LBP. For chronic LBP, acupuncture is more effective than no treatment or sham treatment. Acupuncture is not more effective than other conventional treatments. Acupuncture and dry needling may be useful adjuncts to other therapies/include Asian database. High heterogeneity of included studies. Subjective assessment of clinical relevance.

Zhu et al. (2002) [30]/ChinaLBP9 (426)NRTCMNR2Meta-
analysis
Various controls (sham acu, TENS, medications, or physiotherapy)+NRAcupuncture might be effective for LBP/article in Japanese. Include Japanese database. No subgroup comparison provided.

Ernst and White (1998) [31]/UKBack Pain12 (472)Jadad (10/12)
High
TCM, WesternJudged by six experienced acupuncturists8Meta-
analysis
Various controls (sham acu, no treatment, TENS et al.)NRNRAcupuncture is superior to various control interventions, but insufficient evidence to judge whether it is superior to placebo/no subgroup comparison provided [symptoms improve (+)]

LBP: low back pain; NSLBP: nonspecific low back pain; LIDH: lumbar intervertebral disc herniation; CBRGC: Cochrane Back Review Group Criteria; TCM: traditional Chinese medicine; acu: acupuncture; TENS: transcutaneous electrical nerve stimulation; NR: not reported.
⊚: judged by reviewers; #: conflicting evidence; ⊥: insufficient evidence.
+: more effective than; =: no difference found or not more effective than; −: less effective than.