Effectiveness and Safety of Manufactured Chinese Herbal Formula for Knee Osteoarthritis: Insights from a Systematic Review

Table 3

Methodological quality of the included studies.

Study ID	Random sequence generation	Allocation concealment	Blinding of participants and personnel	Blinding of outcome assessment	Incomplete outcome data	Selective reporting	Other bias
Zuo et al. (2015) [29]	Low risk	Low risk	High risk	High risk	Low risk	Unclear risk	Unclear risk
Huang and Quan (2015) [30]	Unclear risk	Unclear risk	Low risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Cao et al. (2015) [31]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Zhang et al. (2013) [32]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Yi and Ji (2013) [33]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Niu et al. (2013) [34]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Liao (2013) [35]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Li et al. (2013) [36]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Li et al. (2013) [37]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Li et al. (2013) [38]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Chen et al. (2013) [39]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Luo et al. (2012) [40]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Lu et al. (2012) [41]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Li et al. (2012) [42]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Li et al. (2012) [43]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Jiang et al. (2012) [44]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Wang et al. (2011) [45]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Kang et al. (2011) [46]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Yan (2010) [47]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Xiao et al. (2009) [48]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Qi and Xu (2009) [49]	Low risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Li (2009) [50]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
H. B. Liu and J. Liu (2007) [51]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Chen et al. (2007) [52]	High risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Yang et al. (2006) [53]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk
Xu et al. (2004) [54]	Unclear risk	Unclear risk	Unclear risk	Unclear risk	Low risk	Unclear risk	Unclear risk