Xuebijing Injection Promotes M2 Polarization of Macrophages and Improves Survival Rate in Septic Mice

Figure 3

Moderate dose of XBJ (5 mg/mL) upregulated the phosphorylation of JAK1-STAT6 of mouse peritoneal macrophages. Mouse peritoneal macrophages were, respectively, treated with 0 mg/mL, 1 mg/mL, 5 mg/mL, 10 mg/mL, 50 mg/mL, or 100 mg/mL XBJ in the presence of 100 ng/mL LPS for 0 h, 0.5 h, 2 h, 6 h, and 24 h. Expressions of t-JAK1, p-JAK1, t-STAT6, and p-STAT6 were determined by fast activated cell-based ELISA. Data represented the mean ± SEM of independent experiment in triplicate. and versus control group.

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