Xuebijing Injection Promotes M2 Polarization of Macrophages and Improves Survival Rate in Septic Mice

Figure 6

XBJ significantly improved the survival rate of septic mice induced by CLP. Balb/c mice were subjected to lethal sepsis induced by CLP, and either XBJ (4 mg/kg) or normal saline was intramuscularly administered at 0.5 h, 12 h, 24 h, 36 h, 48 h, 60 h, 72 h, 84 h, and 96 h after CLP, respectively. The differences in mortality rate between groups were compared using the Kaplan-Meier method. Different from saline, .