Research Article

ACE Reduces Metabolic Abnormalities in a High-Fat Diet Mouse Model

Table 1

Food intake, body, liver, and adipose tissue weights.

GroupsNaiveControlACE 100ACE 200Curcumin 50

Food intake (g/day/mouse)2.55 ± 0.542.61 ± 0.492.94 ± 0.582.6 ± 0.62.65 ± 0.58

Body weight
 Initial day (g)20.6 ± 0.621.1 ± 0.820.8 ± 0.97 21.0 ± 0.621.23 ± 0.68
 Final day (g)27.1 ± 1.340.7 ± 1.4###36.7 ± 1.637.7 ± 1.438.0 ± 1.2
Liver weight
 Absolute (g)1.08 ± 0.121.68 ± 0.13###1.54 ± 0.121.51 ± 0.151.59 ± 0.07
 Relative (%)3.85 ± 0.494.42 ± 0.34##4.11 ± 0.303.84 ± 0.424.01 ± 0.28
Adipose tissue weight
 Epididymal (g)0.80 ± 0.312.83 ± 0.23###2.37 ± 0.492.38 ± 0.552.42 ± 0.24
 Retroperitoneal (g)0.43 ± 0.231.07 ± 0.15###1.03 ± 0.140.89 ± 0.181.01 ± 0.13
 Visceral (g)0.47 ± 0.181.26 ± 0.31###1.17 ± 0.171.18 ± 0.151.09 ± 0.18
 Total (g)1.80 ± 0.525.17 ± 0.41###4.58 ± 0.564.46 ± 0.624.53 ± 0.34

Data are expressed as mean standard deviation (SD). P < 0.01 and P < 0.001 compared with naive group. P < 0.05, P < 0.01, and P < 0.001 compared with control group. ACE (water extract of Artemisia iwayomogi and Curcuma longa).