Enhanced Protective Effect of the Combination of Uncaria and Semen Raphani on Vascular Endothelium in Spontaneously Hypertensive Rats

Figure 1

The changes of blood pressure and heart rate were detected by noninvasive rat tail method. Systolic pressure (a), diastolic pressure (b), and mean arterial pressure (c) of SHRs kept increasing gradually during the 8-week study. In the period of the first 4 weeks of drug treatment, systolic pressure, diastolic pressure, and mean arterial pressure of SHRs still increased and then decreased significantly. Heart rate (d) of SHRs changed slightly but there was no significance between groups. versus SHRs.

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