Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats

Figure 7

Structural models of berberine as HMG-CoA reductase inhibitor; three plots are represented, (a) proposed binding mode of berberine in the active site of HMG-CoA; (b) atorvastatin bound to crystal structure of HMG-CoA reductase; (c) comparison of putative binding modes of both berberine (red) and atorvastatin (green).

(a)

(b)

(c)