Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats
Table 3
Mean levels of brain oxidative stress and proinflammatory parameters in control, NASH, and berberine treated groups.
Groups
TBARS (nM/mL)
XO (µM/hour)
GPx (IU)
SOD (IU)
GSH (mg/dL)
TNF-alpha (pg/L)
NO (nmole/mL)
Control
12.5 ± 1.2
8.2 ± 0.9
0.02 ± 0.001
8.2 ± 0.07
21 ± 2.1
60.5 ± 3.5
5.6 ± 0.5
Berberine control
10.1 ± 2.1
7.5 ± 0.4
0.02 ± 0.001
9.9 ± 0.5
34 ± 2.3
50.4 ± 6.2
4.3 ± 0.6
NASH group
30.5 ± 3.1
12.3 ± 0.6
0.01 ± 0.007
2.1 ± 0.04
6.4 ± 0.7
205 ± 12.5
54.1 ± 2
Berberine treatment
14.6 ± 1.9
10.1 ± 0.9
0.019 ± 0.0001
7.3 ± 0.2
20.1 ± 0.65
89 ± 10.1
11.5 ± 1
Values are reported as means ± SD of rat groups with different degrees of significance at . Lowest value of significance. Highest value of significance. If two groups have the same letters, it means no significant difference is detected.
