Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats

Table 5

Mean levels of brain parameters in control, NASH, and berberine treated groups.

Groups	AChE (liter moles min^−1 mL^−1)	MAO (IU)	β-amyloid; Aβ40 (pmol/L)	AChE; (liter moles min^−1 g^−1)	MAO; (IU/mg)	β-amyloid; Aβ40 (pmol/L)	IDE
Control	43 ± 2.1^b	8.2 ± 1.1^b	5.6 ± 0.8^b	355 ± 31.1^a	3.1 ± 0.3^a	50 ± 6.5^b	30.6 ± 2.53^b
Berberine control	36 ± 2.1^a	4.3 ± 0.9^a	6 ± 0.1^b	306 ± 21^a	3.2 ± 0.4^a	23 ± 3.4^a	32 ± 3.94^b
NASH group	98 ± 12^d	12 ± 3^c	2.1 ± 0.1^a	898 ± 12^c	8.1 ± 0.9^c	120 ± 22^d	22 ± 0.9^a
Berberine treatment	55 ± 7.5^c	9 ± 1.1^b	6.3 ± 0.9^b	550 ± 75^b	4.3 ± 0.5^b	70 ± 1.9^c	29.3 ± 2.7^a

The superscript letter A: the parameters that were measured in the blood.
The superscript letter B: the parameters that were measured in the brain tissues.
Values are reported as means ± SD of rat groups with different degrees of significance at .
Lowest value of significance.
Highest value of significance.
If two groups have the same letters, it means no significant difference is detected.