Arctigenin from Fructus Arctii (Seed of Burdock) Reinforces Intestinal Barrier Function in Caco-2 Cell Monolayers

Figure 3

Ethyl acetate and chloroform fractions isolated from Fructus Arctii extract reinforced TEER and reduced OVA influx in Caco-2 cells. FAE was fractionated to five fractions, hexane, chloroform, ethyl acetate, butanol, and water fractions. Effects of fractions (200 μg/mL) on TEER values were measured in the cell monolayers, and amount of permeated OVA was also detected in the basolateral side. Each value is presented as mean ± SD (). Bars are significantly different from the control at . Data were analyzed using ANOVA followed by Duncan’s multiple-range test.

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