Identification of Proteins Implicated in the Increased Heart Rate in ShenSongYangXin-Treated Bradycardia Rabbits by iTRAQ-Based Quantitative Proteomics

Table 1

ECG parameters in anesthetized rabbit from sham, model, and SSYX groups.

HR, bpm

P, ms

PR, ms

QRS, ms

QT, ms

QTc, ms

Baseline

Week 6

Baseline

Week 6

Baseline

Week 6

Baseline

Week 6

Baseline

Week 6

Baseline

Week 6

Sham

245 ± 10

249 ± 14

40 ± 0

40 ± 0

63 ± 3

63 ± 3

23 ± 3

23 ± 3

170 ± 4

170 ± 4

102 ± 3

103 ± 2

Model

244 ± 5

40 ± 0

40 ± 0

62 ± 1

60 ± 0

22 ± 2

25 ± 3

163 ± 3

185 ± 11

105 ± 2

93 ± 6

SSYX

258 ± 9

40 ± 0

37 ± 3

63 ± 3

56 ± 3

30 ± 4

27 ± 4

148 ± 4

160 ± 12

97 ± 2

92 ± 4

Data expressed as mean ± SEM. in each group. Electrocardiogram parameters obtained in anesthetized rabbit from sham, model, and SSYX groups before treatment (baseline) and after 6 weeks of treatment. HR: heart rate; P: P wave duration; PQ: PQ interval; QRS: QRS complex duration; QT: QT interval; QTc: corrected QT interval.  QTc = QT/2 √ (RR/100).
versus sham group.
versus model group.