Berberine Regulated Lipid Metabolism in the Presence of C75, Compound C, and TOFA in Breast Cancer Cell Line MCF-7

Figure 5

Mitochondrial function alteration of MCF-7 cells in presence of C75, CC, and TOFA. Mitochondrial function alteration of MCF-7 cells was assayed by mitochondrial deep red real-time determination after pretreatment of C75 (5 μg/mL) (a), CC (4 μg/mL), (b) and TOFA (10 μg/mL) (c) for 3 hours and treatment of berberine (25 μM) for 12 hours. During 12-hour duration, a real-time alteration of mitochondrial function was detected and the curves were presented as percentage of responding value on the initial time point.

(a)

(b)

(c)