Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Tab 3

Review Article

Effectiveness of Acupuncture for Treating Sciatica: A Systematic Review and Meta-Analysis

Table 3

Summary of studies included in the review.

AuthorDesignNumber of subjectsIntervention type (A)Control group (B)Treatment regimenFollow-up periodsOutcome measureResults reportedAdverse events

Wang and La 2004 [20]Parallel, 2 arms40
(23/17)
EADiclofenac sodium 50 mg tid for 7 d1 session once a day for 7 daysNR(1) Laseque's sign angles
(2) VAS
(1) (A) versus (B): 76.67 ± 1.63 versus 70.88 ± 2.11
(2) (A) versus (B): 25.71 ± 2.27 versus 35.33 ± 2.57
NR

Chen et al. 2009 [21]Parallel, 3 arms90
(30/30/30)
WA(1) Nimesulide 0.1 g bid
(2) Acupuncture points injection
3 sessions once daily for 10 daysNR(1) Response rate
(2) PT
(1) (A) significantly better than (B) (, 90% versus 73.33%)
(2) 2.62 ± 0.59 versus 1.54 ± 0.39
NR

Zeng 2012 [22]Parallel, 2 arms60
(30/30)
MA
Pricking blood
Ibuprofen 3 mg bid + Vb2 10 mg tid 2 sessions once daily for 10 daysNR(1) Response rate
(2) BRS-6
(3) VAS
(A) significantly better than (B) (1) (, 83.3% versus 70%)
(2) 4.87 ± 1.50 versus 5.87 ± 1.89
(3) 2.07 ± 1.05 versus 2.70 ± 1.34
NO

Zhang et al. 2008 [23]Parallel, 2 arms194
(98/96)
EAMeloxicam 7.5 mg qd2 sessions once daily for 10 daysNRResponse rate(A) significantly better than (B)
(, 86.53% versus 75%)
3 patients reported hypodermal bleeding in intervention group; 21 patients in control group reported GI problems

Hu et al. 2010 [24]Parallel, 2 arms100
(50/50)
EAMeloxicam 7.5 mg qd2 sessions once daily for 10 daysSix monthResponse rate(A) significantly better than (B)
(, 94% versus 80%);
after half year follow-up 83% versus 70%
5 patients in control group reported GI problems

Du et al. 2009 [25]Parallel, 2 arms62
(32/30)
EADiclofenac sodium 75 mg qd4 sessions 3 times per weekNR(1) JOA for total score
(2) VAS
(1) 20.16 ± 3.54 versus 17.63 ± 3.23
(2) 2.12 ± 1.12 versus 2.10 ± 1.39
NR

Chen 2010 [26]Parallel, 2 arms60
(30/30)
MAIbuprofen 0.2 g tid + prednisone 30 mg qd 2 sessions 3 times per weekNR(1) Response rate
(2) VAS
(3) MOS SF-36
(1) (A) significantly better than (B)
(, 100% versus 83.3%)
(2) VAS 2.78 ± 1.02 versus 4.64 ± 3.21
(3) MOS SF-36 for GH 57.76 ± 15.20 versus 59.07 ± 15.08
2 patients reported hypodermal bleeding in intervention group

Wang 2008 [27]Parallel, 2 arms104
(52/52)
WAIbuprofen 0.6 g bid + Vb1 30 mg tid 2 sessions once daily for 10 daysNRResponse rate(A) significantly better than (B)
(, 96.2% versus 71.2%)
NR

Meng 2014 [28]Parallel, 2 arms60
(30/30)
EA + drugs
(same as control group)
Ibuprofen 20 mg bid + Vb1 30 mg tid2 sessions once daily for 7 daysNR(1) Response rate
(2) VAS
(1) (A) significantly better than (B)
(, 93.33% versus 43.33%)
(2) 3.04 ± 0.53 versus 4.28 ± 0.62
NO

Ren 2013 [29]Parallel, 2 arms60
(30/30)
WA + drugs
(same as control group)
Mannitol 150 mL + dexamethasone 10 mg i.v.gtt and mecobalamin tablets 0.5 mg I.M.1 session once a day for 10 daysNRResponse rate(A) significantly better than (B)
(, 93.3% versus 60%)
NR

Zhao 2004 [30]Parallel, 2 arms60
(30/30)
EASham acupuncture2 sessions once a day for 10 daysNRResponse rate(A) significantly better than (B)
(, 97.7% versus 73.3%)
NO

NR: not reported, EA: electroacupuncture, WA: warm acupuncture, i.v.gtt: intravenous drip, I.M.: intramuscular injection, VAS: Visual Analogue Scale, SF MPQ: Short-Form McGill Pain Questionnaire, PT: pain threshold, JOA: Japanese Orthopaedic Association score, BRS-6: 6-point behavior rating scale, MOS SF-36: the medical outcome study item short form health survey, GI: gastrointestinal, and GH: general health.