Gene symbol
Fold change compared with nonirradiated and untreated control Entrez gene
Gene description Untreated NAC TCM NAC : TCM HMOX1 1.12 1.02 1.07 4.80* 3162 Heme oxygenase (decycling) 1 MT1E 0.76* 0.61* 0.36* 15.70* 4493 Metallothionein 1E MT2A 1.22 0.79 0.74* 10.41* 4502 Metallothionein 2A G6PD 1.24 1.20 1.83* 2.81* 2539 Glucose-6-phosphate dehydrogenase NQO2 1.15 1.32 1.35* 1.58* 4835 NAD(P)H Dehydrogenase, quinone 2 TXNRD1 0.43* 0.85 3.07* 3.14* 7296 Thioredoxin reductase 1 UGT1A10 1.02 1.23 2.25* 1.59* 54659 UDP Glucuronosyltransferase 1 family, polypeptide A10 MT1IP 1.55 1.70* 1.11 12.99* 644314 Metallothionein 1IP (pseudogene) MT1X 1.82* 1.84* 1.51* 10.50* 4501 Metallothionein 1X GADD45G 1.13 1.07 1.01 1.53* 10912 Growth arrest and DNA damage inducible gamma RAD9A 0.98 1.11 1.29 2.06* 5883 RAD9 homolog A XPC 1.18 1.47* 1.57* 1.39* 7508 Xeroderma pigmentosum, complementation group C XRCC1 1.01 1.50* 1.46* 1.38* 7515 X-ray repair complementing defective Repair in Chinese hamster cells 1 JUND 1.81* 1.87* 2.43* 5.02* 3727 Jun D protooncogene SIRT1 0.69* 0.76* 1.03 0.87 23411 Sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae ) PPARD 0.86 0.83 0.50* 1.85* 5467 Peroxisome proliferator-activated receptor delta RELA 1.27 1.04 1.54* 1.86* 5970 v-Rel reticuloendotheliosis viral oncogene homolog A (avian) RELB 1.136 1.04 1.26 2.30* 5971 v-Rel reticuloendotheliosis viral oncogene homolog B NFKB2 1.10 1.10 1.50* 2.12* 4791 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) TNFA1P3 0.76* 0.68* 0.91 1.25* 7128 Tumor necrosis factor, alpha-induced protein 3 NFKBIA 0.83 0.96 1.01 1.25* 4792 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha CXCL1 1.72* 0.54* 0.29* 0.27* 2919 Chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) CXCL2/CXCL3 2.13* 0.91 0.55* 0.54* 2920∣2921 Chemokine (C-X-C motif) ligand 2/chemokine (C-X-C motif) ligand 3 CXCL6 1.22 1.04 0.65* 0.69* 6372 Chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) CXCL14 0.91 1.17 0.67* 0.51* 9547 Chemokine (C-X-C motif) ligand 14 CCL18 0.96 1.03 0.73 0.38* 6362 Chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) CCL20 1.17 0.42* 0.42* 0.49* 6364 Chemokine (C-C motif) ligand 20 FADD 0.99 0.75* 0.97 0.70* 8772 Fas- (TNFRSF6-) associated via the death domain CASP1 0.78 0.54* 0.44* 0.44* 834 Caspase 1, apoptosis-related cysteine peptidase (interleukin-1, beta, convertase) CASP8 0.81 0.53* 0.58* 0.59* 841 Caspase 8, apoptosis-related cysteine peptidase CASP10 0.97 1.08 1.03 0.70* 843 Caspase 10, apoptosis-related cysteine peptidase SP1 1.15 1.51* 1.61* 1.82* 6667 Sp1 transcription factor STAT3 0.92 1.31* 1.22 1.32* 6774 Signal transducer and activator of transcription 3 (acute-phase response factor) CEBPB 1.5* 1.03 1.25 2.22* 1051 CCAAT/enhancer binding protein, beta EGFR 0.74* 0.95 1.07 1.48* 1956 Epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) IL1B 0.96 0.78 2.93* 1.25* 3553 Interleukin-1, beta IL1R1 0.91 0.98 1.44* 1.54* 3554 Interleukin-1 receptor, type I TNFS10 0.93 0.89 0.62* 0.46* 8743 Tumor necrosis factor (ligand) superfamily, member 10 IRZAK1BP1 1.01 0.86 0.68* 0.52* 134728 Interleukin-1 receptor-associated kinase 1 binding protein 1 IRAK2 0.9 1.02 1.18 1.73* 3656 Interleukin-1 receptor-associated kinase 2 MYD88 0.65* 0.82 0.76* 1.10 4615 Myeloid differentiation primary response gene (88) CHUK 0.72* 0.74* 0.939 0.89 1147 Conserved helix-loop-helix ubiquitous kinase NFKBIE 0.96 0.85 0.88 1.59* 4794 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon NFKBIB 0.77* 1.25* 1.33* 1.08 4793 Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta BCL2L10 1.47 1.70 1.09 0.57 10017 BCL2-like 10 (apoptosis facilitator) JUNB 1.10 0.87 1.26 1.65* 3726 Jun B protooncogene CDKN1A 1.16 1.61* 1.60* 2.42* 1026 Cyclin-dependent kinase 1A (p21, Cip1)
