Research Article

The Protective Effects of Areca catechu Extract on Cognition and Social Interaction Deficits in a Cuprizone-Induced Demyelination Model

Figure 3

Areca nut extract (ANE) treatment may prevent the demyelination process in the frontal cortex. Photomicrographs showed MBP immunostaining in the frontal cortex in the control group, CPZ, CPZ + 1% ANE (ANE1), CPZ + 2% ANE (ANE2) groups, respectively. The graph shows the mean MBP-immunostaining optical density in the frontal cortex for each treatment group. Data are represented as the mean ± SEM. . . indicates comparison with the control group while # indicates comparison with the CPZ group.