Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2015 (2015), Article ID 428208, 7 pages
http://dx.doi.org/10.1155/2015/428208
Research Article

In Vivo Evaluation of the Antiasthmatic, Antitussive, and Expectorant Activities and Chemical Components of Three Elaeagnus Leaves

School of Pharmacy, South-Central University for Nationalities, Wuhan 430074, China

Received 10 July 2015; Revised 23 September 2015; Accepted 30 September 2015

Academic Editor: Sergio R. Ambrosio

Copyright © 2015 Yuebin Ge et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. I. Annesi-Maesano, “Epidemiologie de l’asthme,” Revue du Praticien, vol. 55, no. 12, pp. 1295–1298, 2005. View at Google Scholar · View at Scopus
  2. K. F. Chung, G. Caramori, and I. M. Adcock, “Inhaled corticosteroids as combination therapy with β-adrenergic agonists in airways disease: present and future,” European Journal of Clinical Pharmacology, vol. 65, no. 9, pp. 853–871, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. P. A. Akah, A. C. Ezike, S. V. Nwafor, C. O. Okoli, and N. M. Enwerem, “Evaluation of the anti-asthmatic property of Asystasia gangetica leaf extracts,” Journal of Ethnopharmacology, vol. 89, no. 1, pp. 25–36, 2003. View at Publisher · View at Google Scholar · View at Scopus
  4. X. P. Chu, Z. H. Xu, D. Z. Wu et al., “In vitro and in vivo evaluation of the anti-asthmatic activities of fractions from Pheretima,” Journal of Ethnopharmacology, vol. 111, no. 3, pp. 490–495, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. E. J. Yang, J.-S. Lee, C.-Y. Yun et al., “Inhibitory effects of Duchesnea chrysantha extract on ovalbumin-induced lung inflammation in a mouse model of asthma,” Journal of Ethnopharmacology, vol. 118, no. 1, pp. 102–107, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. N. P. Bekker and A. I. Glushenkova, “Components of certain species of the Elaeagnaceae family,” Chemistry of Natural Compounds, vol. 37, no. 2, pp. 97–116, 2001. View at Publisher · View at Google Scholar · View at Scopus
  7. A. Ahmadiani, J. Hosseiny, S. Semnanian et al., “Antinociceptive and anti-inflammatory effects of Elaeagnus angustifolia fruit extract,” Journal of Ethnopharmacology, vol. 72, no. 1-2, pp. 287–292, 2000. View at Publisher · View at Google Scholar · View at Scopus
  8. W. N. Zhang, Z. Y. Liu, and Z. M. Wang, “Advances in the study of active constituents of Shazao,” Chinese Traditional and Herbal Drugs, vol. 17, pp. 41–44, 1986. View at Google Scholar
  9. S.-G. Cao, T. Tanaka, M. Mizuno, and K. Inoue, “Flavonol glycosides from Elaeagnus bockii (Elaeagnaceae),” Natural Product Letters, vol. 15, no. 1, pp. 1–8, 2001. View at Publisher · View at Google Scholar · View at Scopus
  10. S.-G. Cao, T. Tanaka, M. Mizuno, and K. Inoue, “Flavonol glycosides from Elaeagnus lanceollata (Elaeagnaceae),” Natural Product Letters, vol. 15, no. 4, pp. 211–216, 2001. View at Publisher · View at Google Scholar · View at Scopus
  11. M. Ramezani, H. Hosseinzadeh, and N. Daneshmand, “Antinociceptive effect of Elaeagnus angustifolia fruit seeds in mice,” Fitoterapia, vol. 72, no. 3, pp. 255–262, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. H. Hosseinzadeh, M. Ramezani, and N. Namjo, “Muscle relaxant activity of Elaeagnus angustifolia L. fruit seeds in mice,” Journal of Ethnopharmacology, vol. 84, no. 2-3, pp. 275–278, 2003. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Tagahara, J. Koyama, and T. Sugita, “Constituents of the genus Elaeagnus (I): on the constituents of the leaves of Elaeagnus pungens,” Shoyakugaku Zasshi, vol. 35, pp. 340–342, 1981. View at Google Scholar
  14. X. Zhao, H. Huang, and R. L. Zhu, “Liposoluble constituents of leaves of Elaeagnus pungens,” Chinese Traditional Patent Medicine, vol. 28, pp. 403–405, 2006. View at Google Scholar
  15. X. Zhao, R.-L. Zhu, B. Jiang, and H. Huang, “Studies on chemical constituents of cytotoxic fraction from leaves of Elaeagnus pungens,” China Journal of Chinese Materia Medica, vol. 31, no. 6, pp. 472–474, 2006. View at Google Scholar · View at Scopus
  16. M. J. Guo, H. B. Jiang, X. Q. Tian, N. Huang, and J. Huang, “Chemical constituents of the leaves of Elaeagnus pungens thunb,” West China Journal of Pharmaceutical Sciences, vol. 23, pp. 381–383, 2008. View at Google Scholar
  17. P. A. Shen, Pharmacological and Clinical Application of Chinese Material Medica, People's Medical Publishing House, Beijing, China, 2006.
  18. M. S. Li, M. C. Liao, Y. B. Ge, and Z. N. Mei, “Water-soluble chemical constituents from Elaeagnus pungens leaves,” China Journal of Chinese Materia Medica, vol. 37, no. 9, pp. 1224–1226, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. Y.-B. Ge, M.-S. Li, Z.-N. Mei, and G.-Z. Yang, “Two new flavonol glycosides from the leaves of Elaeagnus pungens,” Journal of Asian Natural Products Research, vol. 15, no. 10, pp. 1073–1079, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. B. Ge, J. Q. Liu, and D. F. Su, “In vivo evaluation of the anti-asthmatic, antitussive and expectorant activities of extract and fractions from Elaeagnus pungens leaf,” Journal of Ethnopharmacology, vol. 126, no. 3, pp. 538–542, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. C. Li, Y. B. Ge, D. R. Wan, J. Hu, C. Ying, and L. Y. Wang, “Optimization of extraction condition and quantification of total flavonoids in Elaeagni folium,” Pharmacognosy Journal, vol. 3, no. 26, pp. 8–12, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. Y.-B. Ge, Q. Dai, D.-R. Wan, Q.-H. Liu, and Z.-N. Mei, “Relaxant effect of 1-butanol fraction from Elaeagnus pungens leaf through inhibiting l-type Ca2+ channel on guinea pig tracheal smooth muscle,” Journal of Ethnopharmacology, vol. 150, no. 1, pp. 196–201, 2013. View at Publisher · View at Google Scholar · View at Scopus
  23. F. Zhang, L. Y. Li, Q. Ding, J. Q. Hu, W. F. Long, and D. R. Wan, “Study on identification of three medicinal plant leaves from Elaeagnus genus by infrared spectroscopy,” Journal of Chinese Medicinal Material, vol. 38, no. 1, pp. 70–73, 2015. View at Google Scholar
  24. S. Y. Xu, R. L. Bian, and X. Chen, Pharmacological Experiment Methodology, People's Medical Publishing House, Beijing, China, 1991.
  25. H. Engler and I. Szelenyi, “Tracheal phenol red secretion, a new method for screening mucosecretolytic compounds,” Journal of Pharmacological Methods, vol. 11, no. 3, pp. 151–157, 1984. View at Publisher · View at Google Scholar · View at Scopus
  26. B.-Q. Lin, P.-B. Li, Y.-G. Wang et al., “The expectorant activity of naringenin,” Pulmonary Pharmacology & Therapeutics, vol. 21, no. 2, pp. 259–263, 2008. View at Publisher · View at Google Scholar · View at Scopus
  27. Y. H. Zhang, H. L. Ruan, F. B. Zeng, H. F. Pi, W. Zhao, and J. Z. Wu, “Effective part screening on antitussive, expectorant and anti-asthmatic activities of Fritillaria hupehensis,” Chinese Traditional and Herbal Drugs, vol. 34, pp. 1016–1018, 2003. View at Google Scholar
  28. P.-B. Li, Y. Ma, Y.-G. Wang, and W.-W. Su, “Experimental studies on antitussive, expectorant and antiasthmatic effects of extract from Citrus grandis var. Tomentosa,” China Journal of Chinese Materia Medica, vol. 31, no. 16, pp. 1350–1352, 2006. View at Google Scholar · View at Scopus
  29. S. J. Guan, J. J. Ma, X. Chu et al., “Effects of total flavones from Acanthopanax senticosus on L-type calcium channels, calcium transient and contractility in rat ventricular myocytes,” Phytotherapy Research, vol. 29, pp. 533–539, 2015. View at Publisher · View at Google Scholar · View at Scopus