Antiulcerogenic Activity and Toxicity of Bauhinia holophylla Hydroalcoholic Extract

Table 4

Effect of Bauhinia holophylla (150 mg/kg) on ethanol-induced gastric ulcer area (mm²) in rats that were pretreated with glibenclamide ( channels blocker) or yohimbine (presynaptic adrenoceptors antagonist).

Pretreatment (i.p.)	Treatment (p.o.)	Ulcer area (mm^2)	Gastroprotection (%)
Vehicle	Vehicle	511.51 ± 103.42	—
	B. holophylla	159.52 ± 36.66	68.81
Glibenclamide 5 mg/kg	Vehicle	501.18 ± 258.95	—
	B. holophylla	306.47 ± 83.28	38.85
Yohimbine 3 mg/kg	Vehicle	829.40 ± 264.30	—
	B. holophylla	422.62 ± 174.13	49.04

The results are reported as the mean ± SEM. Unpaired -test, .