Research Article

Determination of Oleanolic and Ursolic Acids in Hedyotis diffusa Using Hyphenated Ultrasound-Assisted Supercritical Carbon Dioxide Extraction and Chromatography

Figure 4

Effect of dynamic extraction time on the extraction yields of OA and UA from H. diffusa using HSC–CO2 and SC–CO2 extractions. Conditions: 0.355 mm, 56°C, 28.2 MPa, 2.3 mL/min, and 12.5% cosolvent (82% aqueous ethanol).