Possible Involvement of µ Opioid Receptor in the Antidepressant-Like Effect of Shuyu Formula in Restraint Stress-Induced Depression-Like Rats

Figure 2

Behavior changes of stressed rats treated with/without Shuyu and/or CTAP. Body weight was monitored before stress (0 day) and just before sacrifice (5 day) (a). Forced swimming test and open field test were performed just before sacrifice. Duration of immobility (b), number of crossings (c), reflecting range of motion, and the number of rearings (d), reflecting exploratory behaviors were recorded as explained in the Materials and Methods. Values are shown as mean ± SEM (each ). ^## compared with the normal control group. compared with RRS group. ^&& compared with Shuyu treated RRS group.

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