Possible Involvement of µ Opioid Receptor in the Antidepressant-Like Effect of Shuyu Formula in Restraint Stress-Induced Depression-Like Rats

Table 1

Peaks	Constituents	Concen. (mg/g)	Linearity	LOD (g/L)	LOQ (g/L)	CV (%)
1	paeoniflorin	6.01 ± 0.1	(6.74–67.4 g/mL)	3.2	7.2	6.21
2	liquiritin	1.6 ± 0.03	(4.84–48.4 g/mL)	1.8	4.9	5.23
3	ammonium glycyrrhetate	6.9 ± 0.06	(7.2–70.2 g/mL)	7.6	13	7.11
4	saikoside a	3.6 ± 0.04	(16.7–167 g/mL)	6.5	12	6.87
5	saikoside d	1.68 ± 0.05	(21.2–212 g/mL)	2.3	7	8.03

Data is expressed as mean ± standard deviation in mg/g of raw herbal materials calculated from three batches.
Inter-batch coefficients of variation (CV) were calculated across three batches of Shuyu preparation.