Pien Tze Huang Inhibits Hypoxia-Induced Angiogenesis via HIF-1α/VEGF-A Pathway in Colorectal Cancer

Figure 3

Effects of PZH on tube formation in HUVECs. (a) HUVECs cells were treated with PZH for 24 h, and then collected HUVECs were cultured in Matrigel coated plates. Representative photomicrographs, at 200x magnification, of three independent experiments are shown. (b) The representative histogram of the area covered by the tube network was quantitated using Image-Pro Plus software. ^#A significant difference compared with normoxic control (). A significant difference compared with hypoxic control ().

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